UC San Diego scientists find an auto-signaling mechanism driving the T cell anti-tumor response When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that. Scientists at University of California San Diego have discovered a property of T cells that could inspire new anti-tumor therapeutics. Through a previously undescribed form of cell auto-signaling, T cells were shown to activate themselves in peripheral tissues, fueling their ability to attack tumors. The study, published May 8, 2023 in Immunity, was led by study first author and postdoctoral fellow Yunlong Zhao, PhD, and co-senior authors Enfu Hui, PhD, professor in the School of Biological Sciences at UC San Diego and Jack D. Bui, MD, PhD, professor of pathology at UC San Diego School of Medicine.
Exposing Media, Political, and AI Bias - Fair-Use Open-Source Intelligence