BLUF: Structural parameters were evaluated in patients with open-angle glaucoma (OAG), high myopia (M), and both conditions concurrently. The study found that patients with high myopia showed the least thinning in certain areas, while macular vessel density was highest in the myopia group. These findings could be beneficial for diagnosing glaucoma in individuals with high myopia.
The study aimed to assess the differences in structural parameters in patients with OAG, high myopia, and both conditions together. A total of 42 subjects were included in the study, with 14 in each group. The researchers evaluated the thickness of the retinal nerve fiber layer (RNFL), macular ganglion cell complex (GCC), and vessel density (VD) of the optic nerve head (ONH) and macula.
The results showed that the group with both OAG and high myopia had the lowest thickness of the mean peripapillary RNFL, specifically in the temporal and inferior quadrants. The macular RNFL was thinnest in this group as well. In terms of VD, the myopia group had the highest macular VD in the inferior quadrant at the superficial capillary plexus and choriocapillaris. The myopia group also had the highest VD in the temporal quadrant and total VD of the ONH at the superficial and deep capillary plexus.
The study suggests that the observed decrease in certain structural parameters, such as the peripapillary RNFL thickness and macular VD, could be beneficial for diagnosing glaucoma in individuals with high myopia. Understanding these parameters is important as high myopia is a significant risk factor for glaucoma.